Length variation within intron 2 of the human IL-1 receptor antagonist protein gene (IL1RN)
نویسندگان
چکیده
منابع مشابه
Effects of IL-1 receptor antagonist intron 2 gene polymorphisms on recurrent pregnancy loss in Iranian population
Introduction: Recurrent Pregnancy Loss (RPL) is a heterogeneous disease which consisting of three or more successive abortions before 20 weeks of pregnancy. The cytokines that secreted by Th1 cells (IL-1, TNFα and IFNγ) were described as etiologic factors in RPL. The aim of this study was investigate to association between recurrent pregnancy loss and IL-1 receptor antagonist gene (IL-1RN) intr...
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background uterine leiomyoma (uls) is the most common gynecological tumor and a significant health concern for many women .the interleukin-1 receptor antagonist (il-1ra) is a naturally occurring cytokine inhibiting interleukin- 1 (il-1) activity by binding to the il-1 receptors without signal transduction. objectives the aim of this study was to investigate the association between interleukin-1...
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Objective(s) Deregulation of the immune system through allied factors and cytokine responses are thought to be important contributors to the pathogenesis of asthma. Vitamin D3 and its nuclear receptor appear to be factors that maybe involved in regulating immune responses during the progression of asthma. The aim of this study was to investigate the association between polymorphisms in intron ...
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متن کاملPolymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation.
BACKGROUND Circulating levels of acute phase reactant proteins such as plasma C-reactive protein (CRP) are likely influenced by multiple genes regulating the innate immune response. METHODS AND RESULTS We screened a set of 16 inflammation-related genes for association with CRP in a large population-based study of healthy young adults (n=1627). Results were validated in 2 independent studies (...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1991
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/19.18.5095